True love! It’s been more than a decade since Katherine Heigl seemed on Grey’s Anatomy, however her personality, Izzie Stevens, was once a significant part of Justin Chambers’ departure from the series in March 2020.

Chambers, who performed Alex Karev for 16 seasons on the ABC scientific drama, announced his departure from the show in November 2019. While he ultimate gave the impression at the collection that month, he returned for a voiceover to near the nature’s tale arc. During the March 5, 2020, episode, viewers learned that Alex left his spouse, Jo Wilson (Camilla Luddington), to be with Izzie and their twins, whom she secretly welcomed without Alex knowing. Alex and Izzie, who dated off and on all through the first six seasons, reconnected when he reached out for assist to avoid wasting Meredith (Ellen Pompeo)’s clinical license.

“I like Jo deeply, nonetheless. I believe I all the time will and if it was near to two girls I like, I’d make a choice my spouse. You know I'd, but it’s not just her. Izzie made our kids,” Alex wrote in a letter Meredith. “She had our embryos.”

In his letter to Jo, Alex admitted she merits more.

“This proper right here, this cowardness, it’s officially the worst thing I’ve ever carried out,” he wrote. “It’s about me, it’s now not about you. You deserve so much higher than this. I love you, Jo. I like that you are brilliant and courageous and it doesn't matter what you undergo you by no means let it cling you again. It makes you stronger, kinder. You made me kinder. You love me for precisely for who I used to be and I cherished you. I like you. Maybe it’s not truthful to mention that but it surely’s true. But this could also be true. I’m in love with Izzie.”

While fans were torn by means of the decision, which showrunner Krista Vernoff called “nearly impossible,” Pompeo was a fan.

“For me individually for Karev to go back to the beginning…. was once the best possible tale line,” the actress wrote on Instagram at the time. “It can pay homage to these fantastic first years and the implausible forged …that created a basis so strong that the show is still standing. So let’s no longer be unhappy. As our fearless leader DA always says let’s PULL UP and celebrate the actors the writers and the improbable crew who make this display come to life each week. No topic what the challenge or how tired we all are within the end… you keep us going…..That is value dancing it out over!”

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Grey’s Anatomy airs on ABC Thursdays at 9 p.m. ET.

Scroll thru to revisit Alex and Izzie’s love tale:

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